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Vitamin C post micro-needling - what are the pro's and cons?


The combination of microneedling and vitamin C serum has become a popular skincare trend, promising a dynamic duo for achieving a radiant and youthful complexion. In this blog, we'll delve into the advantages and disadvantages of incorporating vitamin C serum into your microneedling routine, providing a comprehensive overview of this skincare synergy.


  1. Potent Antioxidant Protection: Vitamin C is renowned for its powerful antioxidant properties. When applied topically during microneedling, it helps neutralise free radicals, protecting the skin from environmental damage. This is especially beneficial for individuals seeking to combat signs of aging and maintain a youthful glow.

  2. Collagen Synthesis Boost: Microneedling itself stimulates collagen production, and when coupled with vitamin C, the effects can be synergistic. Vitamin C plays a crucial role in collagen synthesis, contributing to firmer and more elastic skin. This combination can enhance the overall anti-aging benefits of microneedling.

  3. Brightening and Even Skin Tone: Vitamin C is renowned for its skin-brightening effects. When applied during microneedling, it can target hyperpigmentation, sunspots, and uneven skin tone. This makes the combination particularly advantageous for individuals looking to achieve a more luminous complexion.

  4. Reduced Inflammation and Redness: Microneedling can cause temporary inflammation and redness. Vitamin C's anti-inflammatory properties can help alleviate these post-treatment effects, minimizing discomfort and enhancing the recovery process.

  5. Customisable Treatment Plans: Vitamin C serums come in various formulations, allowing for customised treatment plans. Whether addressing aging concerns, hyperpigmentation, or overall skin health, the versatility of vitamin C makes it a valuable addition to microneedling routines.


  1. Potential for Irritation: While vitamin C is generally well-tolerated, some individuals may experience irritation, especially when applied to freshly micro-needled skin. It's crucial to choose a serum with a suitable concentration of vitamin C and to perform a patch test to gauge skin sensitivity.

  2. Stability Challenges: Vitamin C can be unstable and prone to degradation when exposed to light and air. Ensuring the stability of the serum used during microneedling is essential to reap the full benefits of this antioxidant. Look for serums with stabilized forms of vitamin C, such as ascorbic acid or its derivatives.

  3. Cost Considerations: High-quality vitamin C serums can be relatively expensive. Incorporating this step into a microneedling routine may increase overall skincare costs. However, many users find the investment worthwhile for the potential benefits.

  4. Complex Skincare Routine: Microneedling, when combined with vitamin C, adds an extra step to your skincare routine. Some individuals may find this cumbersome, especially if they prefer a more streamlined approach. It's important to consider personal preferences and lifestyle when incorporating these treatments.

The combination of microneedling and vitamin C serum offers a promising avenue for achieving radiant and healthy skin. While the advantages are substantial, it's essential to be aware of potential disadvantages and tailor the approach to individual skin needs.

While vitamin C serum is generally considered safe for topical application and is celebrated for its antioxidant and collagen-boosting properties, some arguments suggest a potential link between the use of vitamin C serum and the formation of granulomas post-microneedling. Granulomas are small, often benign, nodules that can form in response to various stimuli, including foreign substances or irritants. It's important to note that the argument surrounding vitamin C serum and granulomas is not universally accepted, and research in this area is limited. Here are some points to consider:

  1. Purity and Formulation: The purity and formulation of the vitamin C serum used play a crucial role. Some formulations may contain additional ingredients or impurities that could trigger a reaction in certain individuals. It's essential to choose a high-quality, well-formulated vitamin C serum and, if possible, perform a patch test to gauge individual skin sensitivity.

  2. Needle Penetration: Microneedling involves creating tiny punctures in the skin to stimulate collagen production. If a vitamin C serum with certain characteristics (e.g., low pH or specific additives) is applied immediately post-microneedling, there could be an increased risk of irritation or an inflammatory response, potentially contributing to the formation of granulomas.

  3. Individual Skin Sensitivity: Skin reactions can vary widely from person to person. Individuals with particularly sensitive skin or a history of adverse reactions may be more prone to developing granulomas in response to certain skincare products, including vitamin C serums.

  4. Contamination or Spoilage: Vitamin C serums can be susceptible to contamination or spoilage, especially if not stored properly. Contaminated products may pose a risk of causing skin reactions, including granuloma formation. Ensuring the freshness and purity of the serum is crucial.

  5. Lack of Consensus in Scientific Literature: It's important to note that as of my last knowledge update in January 2022, there isn't a consensus in the scientific literature regarding a direct link between vitamin C serum and granuloma formation post-microneedling. Research in this area is limited, and more studies are needed to establish a clear connection.

While the potential for vitamin C serum to cause granulomas post-microneedling is a topic of discussion, it is advisable to consult with a qualified skincare professional or dermatologist to determine the most suitable products and procedures for individual skin types and concerns. Additionally, staying informed about the latest research developments in skincare is essential, as the field is continuously evolving.

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